“Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems” published in Advanced Materials

My paper, “Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems,” appeared online in Advanced Materials, the leading weekly materials science journal, today (http://onlinelibrary.wiley.com/doi/10.1002/adma.201303680/abstract). In this work I described the development of a cytocompatible covalently adaptable network based on the aryl and aliphatic hydrazone bonds, the characterization of its viscoelastic properties, and the cellular response to encapsulation. I am extremely proud of this work and believe it represents a genuine step forward in the synthetic scaffolds world. I have already planned and begun executing several follow-up studies and look forward to sharing more as these projects progress. The image below shows a C2C12 myoblast encapsulated in a fast relaxing, mixed, and slow relaxing hydrogel and the beginnings of a myotube, from left to right.

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